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The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots

机译：源自的脂肪组织影响从纵隔和皮下脂肪库中分离的人脂肪基质细胞的生物学潜力

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Camilla Siciliano; Antonella Bordin; Mohsen Ibrahim; Isotta Chimenti; Francesco Cassiano; Ilenia Gatto; Giorgio Mangino; Andrea Coccia; Selenia Miglietta; Daniela Bastianelli; Vincenzo Petrozza; Antonella Calogero; Giacomo Frati; Elena De Falco;
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1. The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots - ScienceDirect [J] . Camilla Siciliano, Antonella Bordin, Mohsen Ibrahim, Stem cell research . 2016,第2期

机译：起源的脂肪组织影响从纵隔和皮下脂肪库分离出的人类脂肪基质细胞的生物潜力-ScienceDirect
2. Depot- and obesity-related differences in adipogenesisAdipocyte hypertrophy and hyperplasia are known to facilitate lipid storage in adipose tissues by increasing adipocyte cell size and number, respectively. Adipogenesis is the process resulting in adipose tissue hyperplasia. Although depot-specific differences and obesity-related modulation of adipocyte size are well documented, available data on adipogenesis and adipose tissue hyperplasia are less conclusive. Most studies support a reduction of adipogenesis in the obese state. Preadipocytes of the subcutaneous fat depot appear to be more responsive to adipogenic stimulation compared with those from visceral fat compartments in most studies. A number of studies support the notion that adipose tissue expansion through hyperplasia reduces ectopic lipid excess and obesity-related complications. Several genetic variants have been identified in the genes coding for adipogenesis-regulating proteins. While some of these variants have been clearly associated with the phenotypes of obesity and obesity-related alterations, available data highlight the importance of considering gene–gene and gene–diet interactions. [J] . Julie. Lessard, André. Tchernof Clinical lipidology. . 2012,第5期

机译：脂肪形成与肥胖相关的差异已知脂肪细胞肥大和增生分别通过增加脂肪细胞的大小和数量来促进脂质在脂肪组织中的存储。脂肪形成是导致脂肪组织增生的过程。尽管已经有很多文献记载了贮库特异性差异和肥胖相关的脂肪细胞大小调节，但有关脂肪形成和脂肪组织增生的可用数据尚无定论。大多数研究支持在肥胖状态下减少脂肪形成。在大多数研究中，与来自内脏脂肪区室的脂肪细胞相比，皮下脂肪库的前脂肪细胞似乎对脂肪刺激更为敏感。许多研究支持这样的观点，即通过增生的脂肪组织扩张可以减少异位脂质过多和肥胖相关的并发症。在编码脂肪形成调节蛋白的基因中已经鉴定出几种遗传变异。尽管其中一些变异与肥胖症的表型和与肥胖有关的改变明显相关，但现有数据突出了考虑基因-基因和基因-饮食相互作用的重要性。
3. Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications [J] . RussoV., YuC., BelliveauP., Stem cells translational medicine. . 2014,第2期

机译：从皮下，网膜和胸腔内脂肪组织储库中分离出的人类脂肪干细胞进行再生应用的比较
4. Transplantation of Human Adipose Tissue-Derived Multi-Lineage Progenitor Cells but not Adipose Tissue-Derived Stromal/Stem Cells Reduces Serum Cholesterol in Hyperlipidemic Watanabe Rabbits [C] . Okura H., Soeda M., Morita M., International Congress on Coronary Artery Disease. . 2013

机译：人的移植脂肪组织衍生的多谱系祖细胞但不是脂肪组织衍生的基质/干细胞减少高脂血症Watanabe兔中的血清胆固醇
5. The effect of Ractopamine stereoisomers on in vitro adipose tissue accretion in bovine subcutaneous and intramuscular adipose tissue depots. [D] . Shields, Thomas H., IV. 2005

机译：莱克多巴胺立体异构体对牛皮下和肌肉内脂肪组织贮库中体外脂肪组织增生的影响。
6. Characterization of stromal vascular fraction and adipose stem cells from subcutaneous, preperitoneal and visceral morbidly obese human adipose tissue depots [O] . Karina Ribeiro Silva, Isis Côrtes, Sally Liechocki, 2012

机译：皮下，腹膜前和内脏病态肥胖人脂肪组织贮库的基质血管部分和脂肪干细胞的特征
7. The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots [O] . Siciliano, Camilla, Bordin, Antonella, Ibrahim, Mohsen, 2016

机译：起源的脂肪组织影响从纵隔和皮下脂肪库分离出的人类脂肪基质细胞的生物潜力

The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots

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